Guaifenesin, a mucoactive drug, acts by loosening mucus in the airways and making coughs more productive. It is used for relief of wet cough and chest congestion due to the common cold, and remains the only legally marketed expectorant in the US (per OTC Monograph). An ingredient in numerous over-the-counter (OTC) cough/cold medications, guaifenesin has a secondary indication for use in stable chronic bronchitis (professional indication). Clinical pharmacology and patient studies support the clinical utility of guaifenesin in respiratory conditions where mucus hypersecretion is prevalent: acute upper respiratory tract infections (URTIs), stable chronic bronchitis, and possibly rhinosinusitis. Guaifenesin has a …

What is chronic bronchitis? Chronic bronchitis is a type of COPD (chronic obstructive pulmonary disease). COPD is a group of lung diseases that make it hard to breathe and get worse over time. The other main type of COPD is emphysema. Most people with COPD have both emphysema and chronic bronchitis, but how severe each type is can be different from person to person. Chronic bronchitis is inflammation (swelling) and irritation of the bronchial tubes. These tubes are the airways that carry air to and from the air sacs in your lungs. The irritation of the tubes causes mucus to …

People with bronchitis have swelling and inflammation in their bronchial tubes, the air passages that link the mouth and nose with the lungs. Symptoms of bronchitis include a cough, wheezing, and difficulty breathing. People may also have trouble clearing heavy mucus or phlegm from their airways. Bronchitis can be acute or chronic. Acute bronchitis usually clears up, but chronic bronchitis is persistent and never completely goes away. Quitting or avoiding smoking can help prevent bronchitis. This article looks at the causes, symptoms, treatments, and prevention of bronchitis. Symptoms Bronchitis can be acute or chronic. If it is acute, it happens …